souseikai global clinical research center

Dermatological Studies

As of 2016, we have conducted 53 systemic transdermal study protocols and 93 topical transdermal study protocols.

Preparations of the investigational transdermal agents that we have conducted include Ointments, Creams, Gels, Lotions, Liquid, Adhesive Preparations, Tape, Plasters, Cataplasm, Shampoo, and Microneedle Patches.

We have conducted many studies involving patch tests (single, multiple) for topical and adhesive preparations in order to assess their skin-irritating nature in accordance with both ICDRG (International Contact Dermatitis Research Group) and Japanese Guidelines. We also are able to conduct light patch tests using UVA and UVB.

One of our expertise is in the study of patients with atopic dermatitis. Depending on the client's needs, we can use SCORAD (Severity Scoring of Atopic Dermatitis), and EASI (Eczema Area and Severity Index), as well as the Japanese Society of Dermatology severity categories for evaluations.

Special Evaluations

  • DPK
  • Bacterial harvest and culture in skin antiseptic agent tests
  • Vasoconstrictive capacity, vasodilatory effects
  • PK/PD of the DDS preparations in all therapeutic areas
  • Adhesion tests
  • Residual drug collection